International Journal of Dentistry Research 2018; 3(3): 63-65 ; DOI:10.31254/dentistry.2018.3301
Total anti-oxidant capacity of saliva in chronic periodontitis patients: A biochemical study
Kumar Vivek1 , Amrita2 , Singh Akanksha3 , Chandra Sourav4
1. Assistant Professor, Department of Periodontology, Hazaribag College of Dental Sciences and Hospital, Demotand, Hazaribag, Jharkhand, India
2. Senior Lecturer, Department of Periodontology, Uttaranchal Dental and Medical Research Institute, Majri Grant, Doiwala, Dehradun, Uttarakhand, India
3. Senior Lecturer, Department of Periodontology, Maharana Pratap Dental College, Kanpur, Uttar Pradesh, India
4. Senior Lecturer, Department of Periodontology, Hazaribag College of Dental Sciences and Hospital, Demotand, Hazaribag, Jharkhand, India
*Author to whom correspondence should be addressed.
Received: 2nd February, 2018 / Accepted: 9th October, 2018 / Published : 30th December, 2018
Background: Periodontitis is an infectious disease of the oral cavity involving the inflammation of the sustaining tissues of teeth. Anti-oxidant has an important role in protection of host against inflammation and infection. Hence, this study evaluated the salivary total anti-oxidant capacity in chronic periodontitis patients and healthy patients. Methods: A total of 40 patients were divided into 2 groups. Group 1 (healthy) consisted of 20 individuals with healthy gingiva of probing depth ≤3mm, GI =<1, PI=<1 and CAL=0 and Group 2 (chronic periodontitis) consisted of 20 individuals who had signs of clinical inflammation and a diagnosis of CP with PPD ≥ 5 mm, GI >1, PI> 1and CAL≥ 3mm. Whole saliva were collected and samples were analyzed for total anti-oxidant capacity (TAOC). The results were analyzed by student t test and Mann– Whitney analysis. Results: The result revealed that the total anti-oxidant capacity of saliva in the healthy group had significantly higher levels than periodontitis group. Conclusion: The level of total anti-oxidant capacity was lower in the saliva of chronic periodontitis patients, which results in early diagnosis and treatment of periodontitis.
Total anti-oxidant capacity, Periodontitis, Saliva.
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